NIL10: A New IL10-Receptor Binding Nanoparticle That Induces Cardiac Protection in Mice and Pigs Subjected to Acute Myocardial Infarction through STAT3/NF-κB Activation

• Päätekijät: Laura Tesoro (Tekijä), Ignacio Hernández (Tekijä), Rafael Ramírez-Carracedo (Tekijä), Javier Díez-Mata (Tekijä), Nunzio Alcharani (Tekijä), Beatriz Jiménez-Guirado (Tekijä), Karina Ovejero-Paredes (Tekijä), Marco Filice (Tekijä), Jose Luis Zamorano (Tekijä), Marta Saura (Tekijä), Carlos Zaragoza (Tekijä), Laura Botana (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2022-09-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

(1) Background: Early response after acute myocardial infarction (AMI) prevents extensive cardiac necrosis, in which inflammation resolution, including expression of anti-inflammatory interleukin-10 (IL-10), may play a key role. (2) Methods: We synthesized NIL10, a micelle-based nanoparticle, to tar...