CD4+CD25hiFOXP3+ Regulatory T Cells and Cytokine Responses in Human Schistosomiasis before and after Treatment with Praziquantel.

• Главные авторы: Yvonne Schmiedel (Автор), Ghyslain Mombo-Ngoma (Автор), Lucja A Labuda (Автор), Jacqueline J Janse (Автор), Brechje de Gier (Автор), Ayôla A Adegnika (Автор), Saadou Issifou (Автор), Peter G Kremsner (Автор), Hermelijn H Smits (Автор), Maria Yazdanbakhsh (Автор)
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• Опубликовано: Public Library of Science (PLoS), 2015-08-01T00:00:00Z.
• Предметы: article
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BACKGROUND:Chronic schistosomiasis is associated with T cell hypo-responsiveness and immunoregulatory mechanisms, including induction of regulatory T cells (Tregs). However, little is known about Treg functional capacity during human Schistosoma haematobium infection. METHODOLOGY:CD4+CD25hiFOXP3+ ce...