Biosafety assessment of delivery systems for clinical nucleic acid therapeutics

• Main Authors: Zhimin Li (Author), Li Zhang (Author), Kai Jiang (Author), Yijing Zhang (Author), Yonglin Liu (Author), Guang Hu (Author), Jie Song (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nucleic acid therapeutics, which involve transferring exogenous genes inside target cells, are a promising clinical treatment option that can regulate gene expression at the transcriptional or post-transcriptional level. Ideally, this kind of treatment modality will not lead to an unwanted immune re...