Biosafety assessment of delivery systems for clinical nucleic acid therapeutics

• Principais autores: Zhimin Li (Autor), Li Zhang (Autor), Kai Jiang (Autor), Yijing Zhang (Autor), Yonglin Liu (Autor), Guang Hu (Autor), Jie Song (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2022-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Nucleic acid therapeutics, which involve transferring exogenous genes inside target cells, are a promising clinical treatment option that can regulate gene expression at the transcriptional or post-transcriptional level. Ideally, this kind of treatment modality will not lead to an unwanted immune re...