Emodin-induced autophagic cell death hinders epithelial-mesenchymal transition via regulation of BMP-7/TGF-β1 in renal fibrosis

We aim to explore the effects of emodin and its mechanisms on renal fibrosis (RF). We firstly modeled adriamycin-induced rat RF with unilateral nephrectomy. In vivo and in vitro pharmacological experiments were performed in this study. The presence of collagen deposition was detected by Masson stain...

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Main Authors: Wei Liu (Author), Renze Gu (Author), Yujiao Lou (Author), Chunfeng He (Author), Qingchuan Zhang (Author), Dongmei Li (Author)
Format: Book
Published: Elsevier, 2021-08-01T00:00:00Z.
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