Total Synthesis and Anti-HIV Activity Evaluation of Desmosdumotin D and Analogues

• Hoofdauteurs: Ying Deng (Auteur), Xiaoping Song (Auteur), Tongtong Yun (Auteur), Zuo Xiang (Auteur), Guanghui Wang (Auteur), Gang Li (Auteur), Yanxin Zhang (Auteur), Yiming Song (Auteur), Qingchao Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The natural product Desmosdumotin D (hereafter referred to as <b>Des-D</b>), isolated from the plant <i>Desmos dumosus</i>, showed potent anti-HIV activity. However, the subsequent pharmacological activity and clinical studies are limited due to the low content of <b>De...