Total Synthesis and Anti-HIV Activity Evaluation of Desmosdumotin D and Analogues

• Main Authors: Ying Deng (Author), Xiaoping Song (Author), Tongtong Yun (Author), Zuo Xiang (Author), Guanghui Wang (Author), Gang Li (Author), Yanxin Zhang (Author), Yiming Song (Author), Qingchao Liu (Author)
• Format: Book
• Published: MDPI AG, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The natural product Desmosdumotin D (hereafter referred to as <b>Des-D</b>), isolated from the plant <i>Desmos dumosus</i>, showed potent anti-HIV activity. However, the subsequent pharmacological activity and clinical studies are limited due to the low content of <b>De...