Aggravation of lipopolysaccharide-induced depressive-like behavior in CCR4-deficient mice

• मुख्य लेखकों: Yuta Hara (लेखक), Tatsuma Honzawa (लेखक), Moeka Kitagawa (लेखक), Ritsuki Sano (लेखक), Kazuhiko Matsuo (लेखक), Takashi Nakayama (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Increasing evidence indicates that immune abnormalities are associated with the pathogenesis of depression. CCR4 is a chemokine receptor that regulates regulatory T cell (Treg) and Th17 cell migration. Here, using a lipopolysaccharide (LPS)-induced depression mouse model, we demonstrated that CCR4 d...