A Comparative Pharmacology Study Between the Intracolonic and Oral Routes of 5-FU Administration in a Colon Cancer-Bearing Yoshida Sarcoma Rat Model

We prepared a colon cancer-bearing Yoshida sarcoma rat model to examine the dose-response relationship of antitumor activity of intracolonically or orally administered 5-fluorouracil (5-FU; 45, 30, 20, 13, and 8 mg/kg). At doses of ≥20 mg/kg and ≥30 mg/kg, the 5-FU intracolonic and oral administrati...

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Main Authors: Takeshi Goto (Author), Naoko Tomizawa (Author), Eiji Kobayashi (Author), Akio Fujimura (Author)
Format: Book
Published: Elsevier, 2004-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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