Determination of asenapine in presence of its inactive metabolites in human plasma by LC-MS/MS

• Egile Nagusiak: Nirav P. Patel (Egilea), Mallika Sanyal (Egilea), Naveen Sharma (Egilea), Dinesh S. Patel (Egilea), Pranav S. Shrivastav (Egilea), Bhavin N. Patel (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2018-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

A highly selective and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) assay has been described for the determination of asenapine (ASE) in presence of its inactive metabolites N-desmethyl asenapine (DMA) and asenapine-N-glucuronide (ASG). ASE, and ASE 13C-d3, used as internal st...