Skin Tests of a Novel Nicotine Patch, PHK-301p, in Healthy Male Volunteers: Phase I, Placebo-Controlled Study

• Ngā kaituhi matua: Shin Irie (Author), Hiroshi Tsukikawa (Author), Toshitaka Nabeshima (Author), Makiko Usami (Author), Tadaaki Karino (Author), Shuichi Komatsu (Author), Moriaki Akasaki (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2006-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Major local adverse reactions in the nicotine patches are skin reactions. To assess the skin reaction of PHK-301p, a newly developed nicotine patch, we conducted a phase I study that consisted of 2 parts: a skin irritation test (48-h closed patch test) and a photosensitivity test (24-h closed patch...