Platinum complexes of curcumin delivered by dual-responsive polymeric nanoparticles improve chemotherapeutic efficacy based on the enhanced anti-metastasis activity and reduce side effects

• मुख्य लेखकों: Yan Chen (लेखक), Chen Chen (लेखक), Xiaojuan Zhang (लेखक), Chuanchuan He (लेखक), Pengxuan Zhao (लेखक), Minsi Li (लेखक), Ting Fan (लेखक), Ruicong Yan (लेखक), Yao Lu (लेखक), Robert J. Lee (लेखक), Muhammad Waseem Khan (लेखक), Muhammad Sarfraz (लेखक), Xiang Ma (लेखक), Tan Yang (लेखक), Guangya Xiang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2020-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Platinum-based chemotherapy is used for non-small cell lung cancer (NSCLC). However, it has side effects and minimum efficacy against lung cancer metastasis. In this study, platinum-curcumin complexes were loaded into pH and redox dual-responsive nanoparticles (denoted as Pt-CUR@PSPPN) to facilitate...