The application of next-generation sequencing to validate D12S391 microvariation

• Autori principali: Qingxia Zhang (Autore), Jinjie Liu (Autore), He Ren (Autore), Shuai Sun (Autore), Yi Zhao (Autore), Chong Chen (Autore), Li Jia (Autore), Yacheng Liu (Autore), Jiangwei Yan (Autore)
• Natura: Libro
• Pubblicazione: Wolters Kluwer Medknow Publications, 2018-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Objective: In a paternity case, the D12S391 locus was reported as a mismatch. To confirm the existence of mutations and mutations come from father or mother. Methods: STR and next-generation sequencing technology were used to validate the sequence. Results: NGS showed the loss of one adenine between...