Inhibition of BMP4 and Alpha Smooth Muscle Actin Expression in LX-2 Hepatic Stellate Cells by BMP4-siRNA Lipid Based Nanoparticle
Purpose: To develop and characterize vitamin A (VA)-coupled liposomes for the targeted delivery of BMP4-siRNA to hepatic stellate cells (HSC). VA was selected to increase the uptake by HSC based on their function in the storage of VA. Methods: DOTAP/DOPE liposomes were prepared by film hydration met...
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Main Authors: | , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2018-03-01T00:00:00Z.
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A1234.567 |
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