Hepatitis B virus downregulates vitamin D receptor levels in hepatoma cell lines, thereby preventing vitamin D-dependent inhibition of viral transcription and production

• Päätekijät: Neta Gotlieb (Tekijä), Irena Tachlytski (Tekijä), Yelena Lapidot (Tekijä), Maya Sultan (Tekijä), Michal Safran (Tekijä), Ziv Ben-Ari (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2018-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Vitamin D is a key immune-modulator that plays a role in the innate and adaptive immune systems. Certain pathogens impair the immune defense by downregulating the vitamin D receptor (VDR) pathway. Low serum levels of vitamin D are associated with increased hepatitis B virus (HBV)...