In situ metabolomics in nephrotoxicity of aristolochic acids based on air flow-assisted desorption electrospray ionization mass spectrometry imaging

• Hoofdauteurs: Zhonghua Wang (Auteur), Bingshu He (Auteur), Yaqi Liu (Auteur), Meiling Huo (Auteur), Wenqing Fu (Auteur), Chunyan Yang (Auteur), Jinfeng Wei (Auteur), Zeper Abliz (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2020-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Understanding of the nephrotoxicity induced by drug candidates is vital to drug discovery and development. Herein, an in situ metabolomics method based on air flow-assisted desorption electrospray ionization mass spectrometry imaging (AFADESI-MSI) was established for direct analysis of metabolites i...