Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation

• Egile Nagusiak: Edy Meiyanto (Egilea), Herwandhani Putri (Egilea), Yonika Arum Larasati (Egilea), Rohmad Yudi Utomo (Egilea), Riris Istighfari Jenie (Egilea), Muthi Ikawati (Egilea), Beni Lestari (Egilea), Noriko Yoneda-Kato (Egilea), Ikuko Nakamae (Egilea), Masashi Kawaichi (Egilea), Jun-Ya Kato (Egilea)
• Formatua: Liburua
• Argitaratua: Tabriz University of Medical Sciences, 2019-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Purpose: Pentagamavunon-1 (PGV-1) is a curcumin analogue that shows cytotoxic activity in various cancer cells. In this study, we evaluated the effect of PGV-1 on a highly metastatic breast cancer cell line, the 4T1 cells, as an anti-metastatic and anti-proliferative agent. Methods: Cell viability w...