Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation

• Main Authors: Edy Meiyanto (Author), Herwandhani Putri (Author), Yonika Arum Larasati (Author), Rohmad Yudi Utomo (Author), Riris Istighfari Jenie (Author), Muthi Ikawati (Author), Beni Lestari (Author), Noriko Yoneda-Kato (Author), Ikuko Nakamae (Author), Masashi Kawaichi (Author), Jun-Ya Kato (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Pentagamavunon-1 (PGV-1) is a curcumin analogue that shows cytotoxic activity in various cancer cells. In this study, we evaluated the effect of PGV-1 on a highly metastatic breast cancer cell line, the 4T1 cells, as an anti-metastatic and anti-proliferative agent. Methods: Cell viability w...