Synergetic Effect of rHDL and LXR Agonist on Reduction of Atherosclerosis in Mice

• Главные авторы: Emily E. Morin (Автор), Yanhong Guo (Автор), Hongliang He (Автор), Wenmin Yuan (Автор), Whitney N. Souery (Автор), Maria V. Fawaz (Автор), Yuqing Eugene Chen (Автор), Anna Schwendeman (Автор)
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• Опубликовано: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Предметы: article
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High-density lipoproteins (HDLs) are unique in that they play an important role in the reverse cholesterol transport process. However, reconstituted HDL (rHDL) infusions have demonstrated limited beneficial effect in clinical practice. This is perhaps a consequence of the limited cholesterol efflux...