Synergetic Effect of rHDL and LXR Agonist on Reduction of Atherosclerosis in Mice

• Main Authors: Emily E. Morin (Author), Yanhong Guo (Author), Hongliang He (Author), Wenmin Yuan (Author), Whitney N. Souery (Author), Maria V. Fawaz (Author), Yuqing Eugene Chen (Author), Anna Schwendeman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

High-density lipoproteins (HDLs) are unique in that they play an important role in the reverse cholesterol transport process. However, reconstituted HDL (rHDL) infusions have demonstrated limited beneficial effect in clinical practice. This is perhaps a consequence of the limited cholesterol efflux...