Synthesized natural peptides from amphibian skin secretions increase the efficacy of a therapeutic vaccine by recruiting more T cells to the tumour site

• मुख्य लेखकों: Xuan Pan (लेखक), Bowei Ma (लेखक), Xinchao You (लेखक), Shu Chen (लेखक), Jialing Wu (लेखक), Tianfang Wang (लेखक), Shelley F. Walton (लेखक), Jianwei Yuan (लेखक), Xiaolian Wu (लेखक), Guoqiang Chen (लेखक), Yuejian Wang (लेखक), Guoying Ni (लेखक), Xiaosong Liu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2019-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Therapeutic vaccines against cervical cancer remain ineffective. Previously, we demonstrated that blocking the signalling of a cytokine, interleukin 10, at the time of immunisation elicited significantly higher numbers of antigen specific T cells and inhibited tumour growth in mi...