Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing

Abstract Background In cystic fibrosis (CF), impaired immune cell responses, driven by the dysfunctional CF transmembrane conductance regulator (CFTR) gene, may determine the disease severity but clinical heterogeneity remains a major therapeutic challenge. The characterization of molecular mechanis...

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Main Authors: Justin E. Ideozu (Author), Vittobai Rangaraj (Author), Hiam Abdala-Valencia (Author), Xi Zhang (Author), Manoj Kandpal (Author), Marc A. Sala (Author), Ramana V. Davuluri (Author), Hara Levy (Author)
Format: Book
Published: BMC, 2019-05-01T00:00:00Z.
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