Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing

• Κύριοι συγγραφείς: Justin E. Ideozu (Συγγραφέας), Vittobai Rangaraj (Συγγραφέας), Hiam Abdala-Valencia (Συγγραφέας), Xi Zhang (Συγγραφέας), Manoj Kandpal (Συγγραφέας), Marc A. Sala (Συγγραφέας), Ramana V. Davuluri (Συγγραφέας), Hara Levy (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: BMC, 2019-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background In cystic fibrosis (CF), impaired immune cell responses, driven by the dysfunctional CF transmembrane conductance regulator (CFTR) gene, may determine the disease severity but clinical heterogeneity remains a major therapeutic challenge. The characterization of molecular mechanis...