Characterizing metabolic drivers of Clostridioides difficile infection with activity-based hydrazine probes

• Những tác giả chính: Katelyn A. Bustin (Tác giả), Arwa Abbas (Tác giả), Xie Wang (Tác giả), Michael C. Abt (Tác giả), Joseph P. Zackular (Tác giả), Megan L. Matthews (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Many enzymes require post-translational modifications or cofactor machinery for primary function. As these catalytically essential moieties are highly regulated, they act as dual sensors and chemical handles for context-dependent metabolic activity. Clostridioides difficile is a major nosocomial pat...