The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain

The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain

<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor receptor (EGFR), a member of the ErbB family of receptors, is a transmembrane tyrosine kinase (TK) activated by the binding of extracellular ligands of the EGF-family and involved in triggering the MAPK si...

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Main Authors: Delvenne Philippe (Author), Boniver Jacques (Author), Pauly Marc (Author), Berchem Guy (Author), Kayser Jacques (Author), Faber Carlo (Author), Begon Dominique Y (Author), Chambeau Laetitia (Author), Metzger Brigitte (Author), Dicato Mario (Author), Wenner Thomas (Author)
Format: Book
Published: BMC, 2011-10-01T00:00:00Z.
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3rd Floor Main Library

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