The human epidermal growth factor receptor (EGFR) gene in European patients with advanced colorectal cancer harbors infrequent mutations in its tyrosine kinase domain

• Main Authors: Delvenne Philippe (Author), Boniver Jacques (Author), Pauly Marc (Author), Berchem Guy (Author), Kayser Jacques (Author), Faber Carlo (Author), Begon Dominique Y (Author), Chambeau Laetitia (Author), Metzger Brigitte (Author), Dicato Mario (Author), Wenner Thomas (Author)
• 格式: 圖書
• 出版: BMC, 2011-10-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The epidermal growth factor receptor (EGFR), a member of the ErbB family of receptors, is a transmembrane tyrosine kinase (TK) activated by the binding of extracellular ligands of the EGF-family and involved in triggering the MAPK si...