Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short-Acting Bronchodilators in Paediatric Asthma Patients

• मुख्य लेखकों: Malgorzata Labuda (लेखक), Sophie Laberge (लेखक), Julie Brière (लेखक), Denis Bérubé (लेखक), Patrick Beaulieu (लेखक), Tomi Pastinen (लेखक), Maja Krajinovic (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2011-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Short-acting b2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. The aim of this study was to test whether genetic variants in PDE4D gene, a key regulator of b2-adrenoceptor-induced cAMP turnover in airway smooth muscle cells, affect the response to sh...