Phosphodiesterase Type 4D Gene Polymorphism: Association with the Response to Short-Acting Bronchodilators in Paediatric Asthma Patients

• Hoofdauteurs: Malgorzata Labuda (Auteur), Sophie Laberge (Auteur), Julie Brière (Auteur), Denis Bérubé (Auteur), Patrick Beaulieu (Auteur), Tomi Pastinen (Auteur), Maja Krajinovic (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2011-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Short-acting b2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. The aim of this study was to test whether genetic variants in PDE4D gene, a key regulator of b2-adrenoceptor-induced cAMP turnover in airway smooth muscle cells, affect the response to sh...