<it>SCN5A </it>allelic expression imbalance in African-Americans heterozygous for the common variant p.Ser1103Tyr

• Главные авторы: Levy Bruce P (Автор), Lewis Adele (Автор), Wang Lily (Автор), Kunic Jennifer (Автор), Killen Stacy AS (Автор), Ackerman Michael J (Автор), George Alfred L (Автор)
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• Опубликовано: BMC, 2010-05-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background</p> <p>Heterozygous and homozygous carriers of <it>SCN5A</it>-p.Ser1103Tyr, a common genetic variant with functional effects among African-Americans, have an increased risk of sudden death. We hypothesized that some heterozygous...