<it>SCN5A </it>allelic expression imbalance in African-Americans heterozygous for the common variant p.Ser1103Tyr

• Main Authors: Levy Bruce P (Author), Lewis Adele (Author), Wang Lily (Author), Kunic Jennifer (Author), Killen Stacy AS (Author), Ackerman Michael J (Author), George Alfred L (Author)
• Format: Book
• Published: BMC, 2010-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Heterozygous and homozygous carriers of <it>SCN5A</it>-p.Ser1103Tyr, a common genetic variant with functional effects among African-Americans, have an increased risk of sudden death. We hypothesized that some heterozygous...