Frequent low-impact exposure to THC during adolescence causes persistent sexually dimorphic alterations in the response to viral infection in mice

• Glavni autori: Hye-Lim Lee (Autor), Erica Squire (Autor), Yannick Fotio (Autor), Alex Mabou Tagne (Autor), Jungyeon Lee (Autor), John Jeongwoo Yoon (Autor), Yedam Hong (Autor), Laura Hyunseo Kim (Autor), Kwang-Mook Jung (Autor), Daniele Piomelli (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2024-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Adolescent exposure to Δ9-tetrahydrocannabinol (THC) has enduring effects on energy metabolism and immune function. Prior work showed that daily administration of a low-impact dose of THC (5 mg/kg, intraperitoneal) during adolescence alters transcription in adult microglia and disrupts their respons...