The combination of RPA-CRISPR/Cas12a and Leptospira IgM RDT enhances the early detection of leptospirosis.

• Main Authors: Sirawit Jirawannaporn (Author), Umaporn Limothai (Author), Sasipha Tachaboon (Author), Janejira Dinhuzen (Author), Patcharakorn Kiatamornrak (Author), Watchadaporn Chaisuriyong (Author), Nattachai Srisawat (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Lack of available sensitive point-of-care testing is one of the primary obstacles to the rapid diagnosis of leptospirosis. The purpose of this study was to test the performance of two point-of-care tests, a clustered regularly interspaced short palindromic repeat (CRIS...