The combination of RPA-CRISPR/Cas12a and Leptospira IgM RDT enhances the early detection of leptospirosis.

• Autores principales: Sirawit Jirawannaporn (Autor), Umaporn Limothai (Autor), Sasipha Tachaboon (Autor), Janejira Dinhuzen (Autor), Patcharakorn Kiatamornrak (Autor), Watchadaporn Chaisuriyong (Autor), Nattachai Srisawat (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2023-08-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

<h4>Background</h4>Lack of available sensitive point-of-care testing is one of the primary obstacles to the rapid diagnosis of leptospirosis. The purpose of this study was to test the performance of two point-of-care tests, a clustered regularly interspaced short palindromic repeat (CRIS...