How to Achieve Sufficient Endogenous Insulin Suppression in Euglycemic Clamps Assessing the Pharmacokinetics and Pharmacodynamics of Long-Acting Insulin Preparations Employing Healthy Volunteers

• Asıl Yazarlar: Hui Liu (Yazar), Ting Li (Yazar), Hongling Yu (Yazar), Jiaqi Li (Yazar), Huiwen Tan (Yazar), Yerong Yu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

The therapeutic effect of basal insulin analogs will be sustained at a rather low insulin level. When employing healthy volunteers to assess the pharmacokinetics (PK) and pharmacodynamics (PD) of long-acting insulin preparations by euglycemic clamp techniques, endogenous insulin cannot be ignored an...