Phase I Trial to Evaluate the Tolerance, Pharmacokinetics and Efficacy of the Broad-Spectrum ErbB Family Inhibitor Larotinib Mesylate in Patients With Advanced Solid Tumors
Background: The presented phase I, first-in-human study evaluated the tolerance, pharmacokinetics, and preliminary efficacy of larotinib mesylate in patients with advanced solid tumors.Methods: Cancer patients were assigned to receive larotinib mesylate at 50-400 mg dose levels until disease progres...
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Main Authors: | , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2021-02-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |