Phase I Trial to Evaluate the Tolerance, Pharmacokinetics and Efficacy of the Broad-Spectrum ErbB Family Inhibitor Larotinib Mesylate in Patients With Advanced Solid Tumors

Background: The presented phase I, first-in-human study evaluated the tolerance, pharmacokinetics, and preliminary efficacy of larotinib mesylate in patients with advanced solid tumors.Methods: Cancer patients were assigned to receive larotinib mesylate at 50-400 mg dose levels until disease progres...

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Main Authors: Jingrui Liu (Author), Hong Zhang (Author), Xiaoxue Zhu (Author), Hong Chen (Author), Xiaojiao Li (Author), Yanhua Ding (Author)
Format: Book
Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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