High-Fat Breakfast Increases Bioavailability of Albendazole Compared to Low-Fat Breakfast: Single-Dose Study in Healthy Subjects

• Главные авторы: Dolores Ochoa (Автор), Miriam Saiz-Rodríguez (Автор), Esperanza González-Rojano (Автор), Manuel Román (Автор), Sergio Sánchez-Rojas (Автор), Aneta Wojnicz (Автор), Ana Ruiz-Nuño (Автор), Alfredo García-Arieta (Автор), Francisco Abad-Santos (Автор)
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• Опубликовано: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Предметы: article
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Purpose: Albendazole is a benzimidazole carbamate drug with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. It has been described that the administration with meals increases albendazole absorption. Our aim was to compare the systemic exposure in healthy volunteers o...