High-Fat Breakfast Increases Bioavailability of Albendazole Compared to Low-Fat Breakfast: Single-Dose Study in Healthy Subjects

• Main Authors: Dolores Ochoa (Author), Miriam Saiz-Rodríguez (Author), Esperanza González-Rojano (Author), Manuel Román (Author), Sergio Sánchez-Rojas (Author), Aneta Wojnicz (Author), Ana Ruiz-Nuño (Author), Alfredo García-Arieta (Author), Francisco Abad-Santos (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Albendazole is a benzimidazole carbamate drug with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. It has been described that the administration with meals increases albendazole absorption. Our aim was to compare the systemic exposure in healthy volunteers o...