High-Fat Breakfast Increases Bioavailability of Albendazole Compared to Low-Fat Breakfast: Single-Dose Study in Healthy Subjects

• Hauptverfasser: Dolores Ochoa (Verfasst von), Miriam Saiz-Rodríguez (Verfasst von), Esperanza González-Rojano (Verfasst von), Manuel Román (Verfasst von), Sergio Sánchez-Rojas (Verfasst von), Aneta Wojnicz (Verfasst von), Ana Ruiz-Nuño (Verfasst von), Alfredo García-Arieta (Verfasst von), Francisco Abad-Santos (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Schlagworte: article
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Purpose: Albendazole is a benzimidazole carbamate drug with anthelmintic and antiprotozoal activity against intestinal and tissue parasites. It has been described that the administration with meals increases albendazole absorption. Our aim was to compare the systemic exposure in healthy volunteers o...