USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea

• Главные авторы: Edward F. Boumil (Автор), Nileyma Castro (Автор), Andrew T. Phillips (Автор), Jon E. Chatterton (Автор), Sean M. McCauley (Автор), Alexey D. Wolfson (Автор), Taisia Shmushkovich (Автор), Marc Ridilla (Автор), Audrey M. Bernstein (Автор)
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• Опубликовано: Elsevier, 2020-09-01T00:00:00Z.
• Предметы: article
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Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deliverable siRNAs [sdRNAs]) are a novel modality for...