USP10 Targeted Self-Deliverable siRNA to Prevent Scarring in the Cornea

• প্রধান লেখক: Edward F. Boumil (লেখক), Nileyma Castro (লেখক), Andrew T. Phillips (লেখক), Jon E. Chatterton (লেখক), Sean M. McCauley (লেখক), Alexey D. Wolfson (লেখক), Taisia Shmushkovich (লেখক), Marc Ridilla (লেখক), Audrey M. Bernstein (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2020-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Ocular scarring after surgery, trauma, or infection leads to vision loss. The transparent cornea is an excellent model system to test anti-scarring therapies. Cholesterol-conjugated fully modified asymmetric small interfering RNAs (siRNAs) (self-deliverable siRNAs [sdRNAs]) are a novel modality for...