In Vitro Hb Production in Β-thalassemia Patients Is Not a Predictor of Clinical Responsiveness to Hydroxyurea

Background: The hematologic response to hydroxyurea (HU) is varied among β-thalassemia (BT) patients. The BCL11A and SOX6 genes are involved in response to HU. This study aimed to investigate the in-vitro responsiveness of HU among BT major patients homozygote for IVSII-1G>A mutation and XmnI sin...

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Main Authors: Mohammad Reza MAHDAVI (Author), Farzin POURFARZAD (Author), Mehrnoush KOSARYAN (Author), Mohammad Taghi AKBARI (Author)
Format: Book
Published: Tehran University of Medical Sciences, 2017-06-01T00:00:00Z.
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