Potential Pharmacokinetic Effect of Chicken Xenobiotic Receptor Activator on Sulfadiazine: Involvement of P-glycoprotein Induction

• Egile Nagusiak: Mei Li (Egilea), Ziyong Xu (Egilea), Wang Lu (Egilea), Liping Wang (Egilea), Yujuan Zhang (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2022-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Studies on pharmacokinetic drug-drug interactions have highlighted the importance of P-glycoprotein (P-gp) because of its involvement in substrate drug transport. This study aimed to investigate the role of chicken xenobiotic receptor (CXR) in the regulation of P-gp and its influences on pharmacokin...