Potential Pharmacokinetic Effect of Chicken Xenobiotic Receptor Activator on Sulfadiazine: Involvement of P-glycoprotein Induction

• Główni autorzy: Mei Li (Autor), Ziyong Xu (Autor), Wang Lu (Autor), Liping Wang (Autor), Yujuan Zhang (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Studies on pharmacokinetic drug-drug interactions have highlighted the importance of P-glycoprotein (P-gp) because of its involvement in substrate drug transport. This study aimed to investigate the role of chicken xenobiotic receptor (CXR) in the regulation of P-gp and its influences on pharmacokin...