Compensative Resistance to Erastin-Induced Ferroptosis in GPX4 Knock-Out Mutants in HCT116 Cell Lines

• Auteurs principaux: Malgorzata Adamiec-Organisciok (Auteur), Magdalena Wegrzyn (Auteur), Lukasz Cienciala (Auteur), Damian Sojka (Auteur), Joanna Nackiewicz (Auteur), Magdalena Skonieczna (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Ferroptosis results from the accumulation of oxidized and damaged lipids which then leads to programmed cell death. This programmed process is iron-dependent, and as a fundamental biological process, plays a crucial role in tissue homeostasis. The ferroptosis molecular pathway depends on self-regula...