One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

• المؤلفون الرئيسيون: Sadahiro Naka (مؤلف), Tadashi Watabe (مؤلف), Thomas Lindner (مؤلف), Jens Cardinale (مؤلف), Kenta Kurimoto (مؤلف), Melissa Moore (مؤلف), Mitsuaki Tatsumi (مؤلف), Yuriko Mori (مؤلف), Eku Shimosegawa (مؤلف), Frank Valla (مؤلف), Hiroki Kato (مؤلف), Frederik L. Giesel (مؤلف)
• التنسيق: كتاب
• منشور في: SpringerOpen, 2021-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [18F]Al...