One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

• প্রধান লেখক: Sadahiro Naka (লেখক), Tadashi Watabe (লেখক), Thomas Lindner (লেখক), Jens Cardinale (লেখক), Kenta Kurimoto (লেখক), Melissa Moore (লেখক), Mitsuaki Tatsumi (লেখক), Yuriko Mori (লেখক), Eku Shimosegawa (লেখক), Frank Valla (লেখক), Hiroki Kato (লেখক), Frederik L. Giesel (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: SpringerOpen, 2021-08-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [18F]Al...