One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

• Κύριοι συγγραφείς: Sadahiro Naka (Συγγραφέας), Tadashi Watabe (Συγγραφέας), Thomas Lindner (Συγγραφέας), Jens Cardinale (Συγγραφέας), Kenta Kurimoto (Συγγραφέας), Melissa Moore (Συγγραφέας), Mitsuaki Tatsumi (Συγγραφέας), Yuriko Mori (Συγγραφέας), Eku Shimosegawa (Συγγραφέας), Frank Valla (Συγγραφέας), Hiroki Kato (Συγγραφέας), Frederik L. Giesel (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: SpringerOpen, 2021-08-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Abstract Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [18F]Al...