High-throughput drug screening to investigate blood-brain barrier permeability in vitro with a focus on breast cancer chemotherapeutic agents

• Asıl Yazarlar: Carolin J. Curtaz (Yazar), Sophia Wucherpfennig (Yazar), Emad Al-Masnaea (Yazar), Saskia-Laureen Herbert (Yazar), Achim Wöckel (Yazar), Patrick Meybohm (Yazar), Malgorzata Burek (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Therapy of cerebral diseases such as brain metastatic breast cancer is still challenging. Due to the blood-brain barrier (BBB), a tight barrier that protects the brain and prevents the passage of many drugs, therapeutically sufficient drug concentrations in the brain are often not achieved. Therefor...