High-throughput drug screening to investigate blood-brain barrier permeability in vitro with a focus on breast cancer chemotherapeutic agents

• Hoofdauteurs: Carolin J. Curtaz (Auteur), Sophia Wucherpfennig (Auteur), Emad Al-Masnaea (Auteur), Saskia-Laureen Herbert (Auteur), Achim Wöckel (Auteur), Patrick Meybohm (Auteur), Malgorzata Burek (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2024-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Therapy of cerebral diseases such as brain metastatic breast cancer is still challenging. Due to the blood-brain barrier (BBB), a tight barrier that protects the brain and prevents the passage of many drugs, therapeutically sufficient drug concentrations in the brain are often not achieved. Therefor...