Therapeutic Potentials of an Artificial Oxygen-Carrier, Liposome-Encapsulated Hemoglobin, for Ischemia/Reperfusion-Induced Cerebral Dysfunction in Rats

• Asıl Yazarlar: Jin Kakehata (Yazar), Taku Yamaguchi (Yazar), Hiroko Togashi (Yazar), Ichiro Sakuma (Yazar), Hiroshi Otani (Yazar), Yuji Morimoto (Yazar), Mitsuhiro Yoshioka (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2010-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We performed this study to elucidate whether a newly developed liposome-encapsulated hemoglobin, TRM-645 (TRM), can prevent cerebral dysfunction resulting from acute ischemic stroke when used as an oxygen carrier. Hippocampal long-term potentiation (LTP) in the perforant path-dentate gyrus synapses...